Midwest NeuroResearch Institute (MNRI) is a provider of preclinical and clinical research services. Our research extends to behavioral, cognitive, sentient, and motor-related effects of drugs of abuse - especially the opioids, GHB, cannabinoids and barbiturates, relative to their impact on specific brain sites and receptors. Of special interest are sites and mechanisms of the ascending DA pathways impacted by these drugs. MNRI research also extends to clinical cases involving neuro-trauma; especially brain injuries that involve these and other neurotoxic agents, including their cause and full extent. As a research provider exclusively, MNRI does not offer medical advice or treatment of any kind to patients.